( Extra-label means using an approved human or animal drug in a way that isn’t listed on the drug’s labeling. Also, the labeling includes information on how to use the drug in people, not in cats. However, the human-approved mirtazapine products haven't been proven to be safe and effective in cats. Several mirtazapine products are FDA-approved for people, which veterinarians can legally use in cats in an extra-label manner. They haven’t been reviewed by FDA to make sure they are safe, effective, properly manufactured, and adequately labeled and packaged. These products aren’t legal and FDA considers them to be unapproved animal drugs. However, some drug compounding pharmacies make transdermal mirtazapine products for cats that are compounded from bulk mirtazapine. ( Drug compounding is the process of combining, mixing, or altering ingredients to create a medication tailored to the needs of an individual animal or a small group of animals.) These products are legal as long as FDA-approved Mirataz is the source of the mirtazapine in the compounded product. Many drug compounding pharmacies offer transdermal mirtazapine products for cats. Compounded Products Made from Bulk Mirtazapine are Unapproved If he stops eating most of his food for several days or doesn’t eat anything for more than 2 days, contact your veterinarian. Cats with kidney disease may be slower at clearing Mirataz from their system, resulting in higher drug levels in the body.Īfter you stop giving Mirataz, your cat may have a decreased appetite. The drug may cause increased liver values. Veterinarians should use caution when prescribing Mirataz for cats with liver or kidney disease. Vomiting is also a side effect in some cats receiving Mirataz, likely due to them grooming the ointment off their ears and ingesting the drug. He may vocalize more than normal and become hyperactive. You may see skin reactions on your cat’s ears in the area where you apply the ointment (redness is the most frequent reaction). This prevents household members, including other pets, from being accidentally exposed to the ointment and allows time for the drug to be absorbed by your cat. Also, separate your cat from people or other animals in your household for 2 hours after each dose. Throw out the gloves after each use and then wash your hands with soap and water. When applying Mirataz, wear disposable gloves so you don’t accidentally get some of the ointment on your skin. On the second day, apply it to inside of his right ear, and then keep alternating ears for the 2 weeks of treatment. On the first day, apply the ointment to the inside of your cat’s left ear. You can also refer to the drug’s carton for pictures and a measuring ruler. Your veterinarian or trained veterinary staff will show you how to apply it. You apply a 1.5-inch ribbon of Mirataz ointment topically once daily for 14 days, switching between the left and right ears. Scientists don’t know exactly how it works to induce weight gain, but it’s likely due to multiple factors. The active ingredient in Mirataz is mirtazapine. The drug is absorbed transdermally, meaning through the skin. Mirataz is a topical ointment that you apply to the inside (non-hairy) part of your cat’s ear. Although treatment is aimed at managing or, hopefully, curing the underlying disease, medication may be needed to try to stop or slow down the undesired weight loss. For example, cats with kidney or dental disease or those with stomach and intestinal problems often lose weight. Weight loss is often the first sign of illness in cats. Semintra for Controlling High Blood Pressure in Catsįor More Information Mirataz and Elura for Managing Undesired Weight Loss in Cats Mirataz and Elura for Managing Undesired Weight Loss in Cats
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